Endurobol

Basic Information

CAS ID: 317318-70-0
Molecular Formula: C21H18F3NO3S2
Molecular Weight: 453.5 g/mol
Monoisotopic Mass: 453.068 g/mol
Class: Small Molecule
Natural Product: No
Other Names: GW-501516
Analysis: Drug repositioning mechanism analysis

S S N F F F O O OH

Compound Structure and Identifier

InChI: InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27) See All
InChI Key: YDBLKRPLXZNVNB-UHFFFAOYSA-N
Smiles: Cc1cc(SCc2sc(nc2C)c3ccc(cc3)C(F)(F)F)ccc1OCC(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0525 Peroxisome proliferator-activated receptor delta agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 25477952 Target ID T0525
Uniprot ID Peroxisome proliferator-activated receptor delta Name Peroxisome proliferator-activated receptor delta
Model rat Fibrosis Disease Corneal fibrosis
Process I
Process II cells activation,cells proliferation,myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 17543901 Target ID T0525
Uniprot ID Peroxisome proliferator-activated receptor delta Name Peroxisome proliferator-activated receptor delta
Model vitro Fibrosis Disease Cardiac fibrosis
Process I
Process II fibroblasts proliferation,myofibroblasts differentiation
Process III
Mechanism

Reference Record 3

PubMed ID 17346664 Target ID T0525
Uniprot ID Peroxisome proliferator-activated receptor delta Name Peroxisome proliferator-activated receptor delta
Model vitro Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 9803963
ChEMBL: CHEMBL38943