Sapanisertib

Basic Information

CAS ID: 1224844-38-5
Molecular Formula: C15H15N7O
Molecular Weight: 309.3 g/mol
Monoisotopic Mass: 309.1338 g/mol
Class: Small Molecule
Natural Product: No
Other Names: TAK-228 | MLN-0128 | SAPANISERTIB
Analysis: Drug repositioning mechanism analysis

N N O H2N N H2N N N

Compound Structure and Identifier

InChI: InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19) See All
InChI Key: GYLDXIAOMVERTK-UHFFFAOYSA-N
Smiles: CC(C)n1nc(c2ccc3oc(N)nc3c2)c4c(N)ncnc14 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0363 Serine/threonine-protein kinase mTOR inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 25162417 Target ID T0363
Uniprot ID Serine/threonine-protein kinase mTOR Name Serine/threonine-protein kinase mTOR
Model vitro,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 45375953
ChEMBL: CHEMBL3545097