Dibenzazepine

Basic Information

CAS ID: 256-96-2
Molecular Formula: C14H11N
Molecular Weight: 193.3 g/mol
Monoisotopic Mass: 193.0891 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Iminostilbene | 5H-Dibenz[B,F]Azepine
Analysis: Drug repositioning mechanism analysis

NH

Compound Structure and Identifier

InChI: InChI=1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H See All
InChI Key: LCGTWRLJTMHIQZ-UHFFFAOYSA-N
Smiles: N1c2ccccc2C=Cc3ccccc13 See All
Molfile: Download

Related Target

Target ID Name Interaction
T1016 Gamma secretase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 29140985 Target ID T1016
Uniprot ID Gamma secretase Name Gamma secretase
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Notch signaling

Reference Record 2

PubMed ID 25150830 Target ID T1016
Uniprot ID Gamma secretase Name Gamma secretase
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II myofibroblasts activation,fibroblasts proliferation,myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism Targeting TGF-β/Smad2/3 signaling

Related Link

PubChem: 9212
ChEMBL: CHEMBL243596