GW0742

Basic Information

CAS ID: 317318-84-6
Molecular Formula: C21H17F4NO3S2
Molecular Weight: 471.5 g/mol
Monoisotopic Mass: 471.0586 g/mol
Class: Small Molecule
Natural Product: No
Other Names: GW-0742
Analysis: Drug repositioning mechanism analysis

S S N F F F F O O OH

Compound Structure and Identifier

InChI: InChI=1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28) See All
InChI Key: HWVNEWGKWRGSRK-UHFFFAOYSA-N
Smiles: Cc1cc(SCc2sc(nc2C)c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0525 Peroxisome proliferator-activated receptor delta agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 21244753 Target ID T0525
Uniprot ID Peroxisome proliferator-activated receptor delta Name Peroxisome proliferator-activated receptor delta
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II cells apoptosis
Process III
Mechanism

Reference Record 2

PubMed ID 25006409 Target ID T0525
Uniprot ID Peroxisome proliferator-activated receptor delta Name Peroxisome proliferator-activated receptor delta
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 9934458
ChEMBL: CHEMBL38508