Suramin

Basic Information

CAS ID: 145-63-1
Molecular Formula: C51H40N6O23S6
Molecular Weight: 1297.3 g/mol
Monoisotopic Mass: 1296.0469 g/mol
Class: Small Molecule
Natural Product: No
Other Names: NAPHURIDE | SURAMIN SODIUM | CI-1003 | SURAMIN HEXASODIUM
Analysis: Drug repositioning mechanism analysis

NH O NH O NH O NH O NH S O O OH S O O HO S O O OH O NH S O O OH S O O OH S O O HO

Compound Structure and Identifier

InChI: InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80) See All
InChI Key: FIAFUQMPZJWCLV-UHFFFAOYSA-N
Smiles: Cc1ccc(cc1NC(=O)c2cccc(NC(=O)Nc3cccc(c3)C(=O)Nc4cc(ccc4C)C(=O)Nc5ccc(c6cc(cc(c56)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c2)C(=O)Nc7ccc(c8cc(cc(c78)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0138 Sphingosine 1-phosphate receptor 3 antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 19398237 Target ID T0138
Uniprot ID Sphingosine 1-phosphate receptor 3 Name Sphingosine 1-phosphate receptor 3
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II cells migration
Process III
Mechanism

Reference Record 2

PubMed ID 24530413 Target ID
Uniprot ID Name
Model human,rat Fibrosis Disease Liver fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 5361
ChEMBL: CHEMBL265502