Sphingosine 1-phosphate receptor 3

Basic Information


Uniprot ID: Q99500
Secondary ID: Q5SQD8, Q7Z5I2
Symbol: S1PR3
Other Name: EDG3,S1P receptor 3,S1P3,Endothelial differentiation G-protein coupled receptor 3,Sphingosine 1-phosphate receptor Edg-3,S1P receptor Edg-3
Class: Single Protein
Type: pro-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer


Target Classification


Category I Category II Category III
Extracellular G protein-coupled receptor Edg receptor

Related Compound


Target ID Name Interaction
D0267 Suramin antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 25198418 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting CTGF

Reference Record 2

PubMed ID 19398237 Compound ID D0267
CAS 145-63-1 Name Suramin
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II cells migration
Process III
Mechanism