SR6452

Basic Information

CAS ID: 1216744-19-2
Molecular Formula: C18H21ClN2O4S
Molecular Weight: 396.9 g/mol
Monoisotopic Mass: 396.0911 g/mol
Class: Small Molecule
Natural Product: No
Other Names: GSK-4112 | SR6452
Analysis: Drug repositioning mechanism analysis

O O N Cl S N+ O O-

Compound Structure and Identifier

InChI: InChI=1S/C18H21ClN2O4S/c1-18(2,3)25-17(22)12-20(10-13-4-6-14(19)7-5-13)11-15-8-9-16(26-15)21(23)24/h4-9H,10-12H2,1-3H3 See All
InChI Key: WYSLOKHVFKLWOU-UHFFFAOYSA-N
Smiles: CC(C)(C)OC(=O)CN(Cc1ccc(Cl)cc1)Cc2ccc(s2)[N+](=O)[O-] See All
Molfile: Download

Related Target

Target ID Name Interaction
T0529 Nuclear receptor subfamily 1 group D member 1 modulator

Related Fibrosis Property

Reference Record 1

PubMed ID 24497272 Target ID T0529
Uniprot ID Nuclear receptor subfamily 1 group D member 1 Name Nuclear receptor subfamily 1 group D member 1
Model vitro,human,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 50905018
ChEMBL: CHEMBL1961795