2,4,3',5'-tetramethoxystilbene

Basic Information

CAS ID: 24144-92-1
Molecular Formula: C18H20O4
Molecular Weight: 300.4 g/mol
Monoisotopic Mass: 300.1362 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Trans-2,4,3',5'-Tetramethoxystilbene
Analysis: Drug repositioning mechanism analysis

O O O O

Compound Structure and Identifier

InChI: InChI=1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+ See All
InChI Key: JDBCWSHYEQUBLW-AATRIKPKSA-N
Smiles: COc1ccc(\C=C\c2cc(OC)cc(OC)c2)c(OC)c1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0462 Cytochrome P450 1B1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 24477449 Target ID T0462
Uniprot ID Cytochrome P450 1B1 Name Cytochrome P450 1B1
Model rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 24477449 Target ID T0462
Uniprot ID Cytochrome P450 1B1 Name Cytochrome P450 1B1
Model rat Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 22088434 Target ID T0462
Uniprot ID Cytochrome P450 1B1 Name Cytochrome P450 1B1
Model rat Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting RK1/2, p38 MAPK and c-Src

Related Link

PubChem: 5354004
ChEMBL: CHEMBL46909