Cytochrome P450 1B1

Basic Information

Uniprot ID: Q16678
Secondary ID: Q5TZW8, Q93089, Q9H316
Symbol: CYP1B1
Other Name: CYPIB1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Monooxygenase,Oxidoreductase

Target Classification

Category I Category II Category III
Intracellular Enzyme Cytochrome P450

Related Compound

Target ID Name Interaction
D0270 2,4,3',5'-tetramethoxystilbene inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 26928804 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 24477449 Compound ID D0270
CAS 24144-92-1 Name 2,4,3',5'-tetramethoxystilbene
Model rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 24477449 Compound ID D0270
CAS 24144-92-1 Name 2,4,3',5'-tetramethoxystilbene
Model rat Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 22184325 Compound ID
CAS Name
Model mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 22088434 Compound ID D0270
CAS 24144-92-1 Name 2,4,3',5'-tetramethoxystilbene
Model rat Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting RK1/2, p38 MAPK and c-Src