Sonolisib

Basic Information

CAS ID: 502632-66-8
Molecular Formula: C29H35NO8
Molecular Weight: 525.6 g/mol
Monoisotopic Mass: 525.2363 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Sonolisib | PX-866
Analysis: Drug repositioning mechanism analysis

O O O N OH O O O O

Compound Structure and Identifier

InChI: InChI=1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20(32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8,14,18-19,21,34H,1-2,9-13,15H2,3-6H3/b17-14+/t18-,19+,21+,28-,29-/m0/s1 See All
InChI Key: QIUASFSNWYMDFS-NILGECQDSA-N
Smiles: COC[C@H]1OC(=O)\C(=C\N(CC=C)CC=C)\C2=C(O)C(=O)C3=C([C@@H](C[C@@]4(C)[C@H]3CCC4=O)OC(=O)C)[C@@]12C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0954 Phosphoinositide 3-kinase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 24475138 Target ID T0954
Uniprot ID Phosphoinositide 3-kinase Name Phosphoinositide 3-kinase
Model mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 9849735
ChEMBL: CHEMBL411907