NS-018

Basic Information

CAS ID: 1239358-86-1
Molecular Formula: C21H20FN7
Molecular Weight: 389.4 g/mol
Monoisotopic Mass: 389.176 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

F NH N NH N N N N

Compound Structure and Identifier

InChI: InChI=1S/C21H20FN7/c1-14(15-3-5-18(22)6-4-15)26-19-9-16(17-11-25-29(2)13-17)10-20(27-19)28-21-12-23-7-8-24-21/h3-14H,1-2H3,(H2,24,26,27,28)/t14-/m0/s1 See All
InChI Key: UQTPDWDAYHAZNT-AWEZNQCLSA-N
Smiles: CC(C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0357 Tyrosine-protein kinase JAK2 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 24413068 Target ID T0357
Uniprot ID Tyrosine-protein kinase JAK2 Name Tyrosine-protein kinase JAK2
Model vitro,mice Fibrosis Disease Bone marrow fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 46866319
ChEMBL: