15d-PGJ2

Basic Information

CAS ID: 87893-55-8
Molecular Formula: C20H28O3
Molecular Weight: 316.4 g/mol
Monoisotopic Mass: 316.2038 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

O OH O

Compound Structure and Identifier

InChI: InChI=1S/C20H28O3/c1-2-3-4-5-6-10-13-18-17(15-16-19(18)21)12-9-7-8-11-14-20(22)23/h6-7,9-10,13,15-17H,2-5,8,11-12,14H2,1H3,(H,22,23)/b9-7-,10-6+,18-13+/t17-/m0/s1 See All
InChI Key: VHRUMKCAEVRUBK-GODQJPCRSA-N
Smiles: CCCCC\C=C\C=C\1/[C@@H](C\C=C/CCCC(=O)O)C=CC1=O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0526 Peroxisome proliferator-activated receptor gamma agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 24175906 Target ID
Uniprot ID Name
Model vitro Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II fibroblasts migration
Process III
Mechanism

Reference Record 2

PubMed ID 23887394 Target ID
Uniprot ID Name
Model vitro Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III
Mechanism

Reference Record 3

PubMed ID 21765824 Target ID
Uniprot ID Name
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III
Mechanism Targeting PPARγ

Reference Record 4

PubMed ID 17245650 Target ID
Uniprot ID Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 5

PubMed ID 15734787 Target ID T0526
Uniprot ID Peroxisome proliferator-activated receptor gamma Name Peroxisome proliferator-activated receptor gamma
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 5311211
ChEMBL: CHEMBL482477