Apafant

Basic Information

CAS ID: 105219-56-5
Molecular Formula: C22H22ClN5O2S
Molecular Weight: 456 g/mol
Monoisotopic Mass: 455.1183 g/mol
Class: Small Molecule
Natural Product: No
Other Names: WEB 2086 BS | Apafant | WEB-2086
Analysis: Drug repositioning mechanism analysis

N N N Cl O N O S N

Compound Structure and Identifier

InChI: InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3 See All
InChI Key: JGPJQFOROWSRRS-UHFFFAOYSA-N
Smiles: Cc1nnc2CN=C(c3ccccc3Cl)c4cc(CCC(=O)N5CCOCC5)sc4n12 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0142 Platelet-activating factor receptor antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 23826375 Target ID T0142
Uniprot ID Platelet-activating factor receptor Name Platelet-activating factor receptor
Model mice Fibrosis Disease Subretinal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 65889
ChEMBL: CHEMBL280164