Platelet-activating factor receptor

Basic Information


Uniprot ID: P25105
Secondary ID: A3KMC8, A8K2H5
Symbol: PTAFR
Other Name: PAFR
Class: Single Protein
Type: pro-fibrotic
Molecular Function: G-protein coupled receptor,Receptor,Transducer


Target Classification


Category I Category II Category III
Extracellular G protein-coupled receptor Edg receptor

Related Compound


Target ID Name Interaction
D0300 Apafant antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 23826375 Compound ID D0300
CAS 105219-56-5 Name Apafant
Model mice Fibrosis Disease Subretinal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism