TAE226

Basic Information

CAS ID: 761437-28-9
Molecular Formula: C23H25ClN6O3
Molecular Weight: 469 g/mol
Monoisotopic Mass: 468.1677 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

NH O NH N NH O N O N Cl

Compound Structure and Identifier

InChI: InChI=1S/C23H25ClN6O3/c1-25-22(31)16-5-3-4-6-18(16)27-21-17(24)14-26-23(29-21)28-19-8-7-15(13-20(19)32-2)30-9-11-33-12-10-30/h3-8,13-14H,9-12H2,1-2H3,(H,25,31)(H2,26,27,28,29) See All
InChI Key: UYJNQQDJUOUFQJ-UHFFFAOYSA-N
Smiles: CNC(=O)c1ccccc1Nc2nc(Nc3ccc(cc3OC)N4CCOCC4)ncc2Cl See All
Molfile: Download

Related Target

Target ID Name Interaction
T0409 Focal adhesion kinase 1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 23642017 Target ID T0409
Uniprot ID Focal adhesion kinase 1 Name Focal adhesion kinase 1
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II fibroblasts proliferation,fibroblasts differentiation
Process III
Mechanism

Related Link

PubChem: 9934347
ChEMBL: CHEMBL458997