SB366791

Basic Information

CAS ID: 472981-92-3
Molecular Formula: C16H14ClNO2
Molecular Weight: 287.8 g/mol
Monoisotopic Mass: 287.0713 g/mol
Class: Small Molecule
Natural Product: No
Other Names: SB-366791
Analysis: Drug repositioning mechanism analysis

O NH O Cl

Compound Structure and Identifier

InChI: InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ See All
InChI Key: RYAMDQKWNKKFHD-JXMROGBWSA-N
Smiles: COc1cccc(NC(=O)\C=C\c2ccc(Cl)cc2)c1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0163 Transient receptor potential cation channel subfamily V member 1 antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 21641388 Target ID T0163
Uniprot ID Transient receptor potential cation channel subfamily V member 1 Name Transient receptor potential cation channel subfamily V member 1
Model vitro,mice Fibrosis Disease Eye fibrosis
Process I attenue inflammation
Process II myofibroblasts differentiation
Process III
Mechanism

Related Link

PubChem: 667594
ChEMBL: CHEMBL122413