Transient receptor potential cation channel subfamily V member 1

Basic Information


Uniprot ID: Q8NER1
Secondary ID: A2RUA9
Symbol: TRPV1
Other Name: VR1,TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Calcium channel,Calmodulin-binding,Ion channel


Target Classification


Category I Category II Category III
Extracellular Ion channel protein Transient receptor potential channel

Related Compound


Target ID Name Interaction
D0367 SB366791 antagonist
D0368 JYL1421 antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 21641388 Compound ID D0367
CAS 472981-92-3 Name SB366791
Model vitro,mice Fibrosis Disease Eye fibrosis
Process I attenue inflammation
Process II myofibroblasts differentiation
Process III
Mechanism

Reference Record 2

PubMed ID 21641388 Compound ID D0368
CAS 401907-26-4 Name JYL1421
Model vitro,mice Fibrosis Disease Eye fibrosis
Process I attenue inflammation
Process II myofibroblasts differentiation
Process III
Mechanism