SB204741

Basic Information

CAS ID: 152239-46-8
Molecular Formula: C14H14N4OS
Molecular Weight: 286.4 g/mol
Monoisotopic Mass: 286.0888 g/mol
Class: Small Molecule
Natural Product: No
Other Names: SB-204741
Analysis: Drug repositioning mechanism analysis

NH O NH N S N

Compound Structure and Identifier

InChI: InChI=1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19) See All
InChI Key: USFUFHFQWXDVMH-UHFFFAOYSA-N
Smiles: Cc1cc(NC(=O)Nc2ccc3c(ccn3C)c2)sn1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0146 5-hydroxytryptamine receptor 2B inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 21518801 Target ID T0146
Uniprot ID 5-hydroxytryptamine receptor 2B Name 5-hydroxytryptamine receptor 2B
Model vitro,human,mice Fibrosis Disease Systemic sclerosis
Process I
Process II myofibroblasts differentiation,myofibroblasts accumulation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 3277600
ChEMBL: CHEMBL323356