Lactacystin

Basic Information

CAS ID: 133343-34-7
Molecular Formula: C15H24N2O7S
Molecular Weight: 376.4 g/mol
Monoisotopic Mass: 376.1304 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Lactacystin
Analysis: Drug repositioning mechanism analysis

OH NH O HO O S NH O O HO

Compound Structure and Identifier

InChI: InChI=1S/C15H24N2O7S/c1-6(2)10(19)15(11(20)7(3)12(21)17-15)14(24)25-5-9(13(22)23)16-8(4)18/h6-7,9-11,19-20H,5H2,1-4H3,(H,16,18)(H,17,21)(H,22,23)/t7-,9+,10+,11+,15-/m1/s1 See All
InChI Key: DAQAKHDKYAWHCG-RWTHQLGUSA-N
Smiles: CC(C)[C@H](O)[C@]1(NC(=O)[C@H](C)[C@@H]1O)C(=O)SC[C@H](NC(=O)C)C(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T1023 Proteasome inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 21175982 Target ID T1023
Uniprot ID Proteasome Name Proteasome
Model vitro,rat Fibrosis Disease Renal fibrosis
Process I
Process II myofibroblasts differentiation
Process III
Mechanism Targeting Smad

Related Link

PubChem: 6610292
ChEMBL: CHEMBL374308