Dimethylamiloride hydrochloride

Basic Information

CAS ID: 1214-79-5
Molecular Formula: C8H13Cl2N7O
Molecular Weight: 257.7 g/mol
Monoisotopic Mass: 257.0792 g/mol
Class: Small Molecule
Natural Product: No
Other Names: 5-(N,N-Dimethyl)Amiloride Hydrochloride
Analysis: Drug repositioning mechanism analysis

HCl N N NH2 N Cl O NH NH NH2

Compound Structure and Identifier

InChI: InChI=1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H See All
InChI Key: IIUPTHVVXMBJMQ-UHFFFAOYSA-N
Smiles: Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)NC(=N)N See All
Molfile: Download

Related Target

Target ID Name Interaction
T0178 Sodium/hydrogen exchanger 1 antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 19814640 Target ID T0178
Uniprot ID Sodium/hydrogen exchanger 1 Name Sodium/hydrogen exchanger 1
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 11957442
ChEMBL: CHEMBL1256020