Sodium/hydrogen exchanger 1

Basic Information


Uniprot ID: P19634
Secondary ID: B1ALD6, D3DPL4, Q96EM2
Symbol: SLC9A1
Other Name: APNH1,APNH,Na(+)H(+) antiporter, amiloride-sensitive,Na(+)H(+) exchanger 1,NHE-1,Solute carrier family 9 member 1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Calmodulin-binding


Target Classification


Category I Category II Category III
Extracellular Transporter Electrochemical transporter

Related Compound


Target ID Name Interaction
D0403 Dimethylamiloride hydrochloride antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 19814640 Compound ID D0403
CAS 1214-79-5 Name Dimethylamiloride hydrochloride
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism