Pyrazolanthrone

Basic Information

CAS ID: 129-56-6
Molecular Formula: C14H8N2O
Molecular Weight: 220.2 g/mol
Monoisotopic Mass: 220.0637 g/mol
Class: Small Molecule
Natural Product: No
Other Names: SP-600125
Analysis: Drug repositioning mechanism analysis

OH N N

Compound Structure and Identifier

InChI: InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7,17H See All
InChI Key: KRIUNPBAQZGFQA-UHFFFAOYSA-N
Smiles: Oc1c2ccccc2c3N=Nc4cccc1c34 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0344 Mitogen-activated protein kinase 8 inhibitor
T0972 c-Jun N-terminal kinases inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26908192 Target ID T0972
Uniprot ID c-Jun N-terminal kinases Name c-Jun N-terminal kinases
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 19782079 Target ID T0344
Uniprot ID Mitogen-activated protein kinase 8 Name Mitogen-activated protein kinase 8
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II HSCs activation,HSCs proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem:
ChEMBL: CHEMBL1725279