Deazaneplanocin A

Basic Information

CAS ID: 102052-95-9
Molecular Formula: C12H14N4O3
Molecular Weight: 262.3 g/mol
Monoisotopic Mass: 262.1066 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

H2N N N N OH OH OH

Compound Structure and Identifier

InChI: InChI=1S/C12H14N4O3/c13-12-9-7(1-2-14-12)16(5-15-9)8-3-6(4-17)10(18)11(8)19/h1-3,5,8,10-11,17-19H,4H2,(H2,13,14)/t8-,10-,11+/m1/s1 See All
InChI Key: OMKHWTRUYNAGFG-IEBDPFPHSA-N
Smiles: Nc1nccc2c1ncn2[C@@H]3C=C(CO)[C@@H](O)[C@H]3O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0670 Histone-lysine N-methyltransferase EZH2 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 19843474 Target ID T0670
Uniprot ID Histone-lysine N-methyltransferase EZH2 Name Histone-lysine N-methyltransferase EZH2
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSCs differentiation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 73087
ChEMBL: CHEMBL154745