Histone-lysine N-methyltransferase EZH2

Basic Information


Uniprot ID: Q15910
Secondary ID: B2RAQ1
Symbol: EZH2
Other Name: KMT6,ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6
Class: Epigenetics
Type: pro/anti-fibrotic
Molecular Function: Chromatin regulator,Methyltransferase,Repressor,Transferase


Target Classification


Category I Category II Category III
Intracellular Epigenetics Writer

Related Compound


Target ID Name Interaction
D0414 Deazaneplanocin A inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 27081096 Compound ID
CAS Name
Model mice Fibrosis Disease Bone marrow fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 19843474 Compound ID D0414
CAS 102052-95-9 Name Deazaneplanocin A
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II HSCs differentiation
Process III prevenet collagen deposition
Mechanism