Ruboxistaurin

Basic Information

CAS ID: 169939-94-0
Molecular Formula: C28H28N4O3
Molecular Weight: 468.6 g/mol
Monoisotopic Mass: 468.2161 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Arxxant | LY-333531 | Ruboxistaurin
Analysis: Drug repositioning mechanism analysis

N N O NH O N O

Compound Structure and Identifier

InChI: InChI=1S/C28H28N4O3/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34)/t18-/m0/s1 See All
InChI Key: ZCBUQCWBWNUWSU-SFHVURJKSA-N
Smiles: CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c4cn(CCO1)c5ccccc45)c6ccccc26 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0393 Protein kinase C alpha type inhibitor
T0394 Protein kinase C beta type inhibitor
T0396 Protein kinase C gamma type inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 19556521 Target ID T0393
Uniprot ID Protein kinase C alpha type Name Protein kinase C alpha type
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 19556521 Target ID T0394
Uniprot ID Protein kinase C beta type Name Protein kinase C beta type
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 19556521 Target ID T0396
Uniprot ID Protein kinase C gamma type Name Protein kinase C gamma type
Model mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 153999
ChEMBL: CHEMBL91829