Protein kinase C beta type

Basic Information

Uniprot ID:	P05771
Secondary ID:	C5IFJ8
Symbol:	PRKCB
Other Name:	PKCB
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Chromatin regulator,Kinase,Serine/threonine-protein kinase,Transferase

Target Classification

Category I	Category II	Category III
Intracellular	Enzyme	Kinase

Related Compound

Target ID	Name	Interaction
D0416	Ruboxistaurin	inhibitor
D0437	Hispidin	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	19556521	Compound ID	D0416
CAS	169939-94-0	Name	Ruboxistaurin
Model	mice	Fibrosis Disease	Cardiac fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID	18440851	Compound ID	D0437
CAS	555-55-5	Name	Hispidin
Model	vitro	Fibrosis Disease	Renal fibrosis
Process I
Process II	myofibroblasts differentiation
Process III	prevenet collagen deposition
Mechanism