SB223245

Basic Information

CAS ID: 175529-44-9
Molecular Formula: C22H23N5O4
Molecular Weight: 421.5 g/mol
Monoisotopic Mass: 421.175 g/mol
Class: Small Molecule
Natural Product: No
Other Names: SB-223245
Analysis: Drug repositioning mechanism analysis

N N NH O NH O OH O N

Compound Structure and Identifier

InChI: InChI=1S/C22H23N5O4/c1-26-11-14-9-13(7-8-15(14)23-18(22(26)31)10-20(28)29)21(30)27(2)12-19-24-16-5-3-4-6-17(16)25-19/h3-9,18,23H,10-12H2,1-2H3,(H,24,25)(H,28,29)/t18-/m0/s1 See All
InChI Key: PVNQAXDNDZYXIW-SFHVURJKSA-N
Smiles: CN(Cc1nc2ccccc2[nH]1)C(=O)c3ccc4N[C@@H](CC(=O)O)C(=O)N(C)Cc4c3 See All
Molfile: Download

Related Target

Target ID Name Interaction
T1029 Alpha-v beta-3 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 18456735 Target ID T1029
Uniprot ID Alpha-v beta-3 Name Alpha-v beta-3
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Smad2

Related Link

PubChem: 9823503
ChEMBL: CHEMBL50106