Alpha-v beta-3

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: pro-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Other

Related Compound

Target ID Name Interaction
D0434 SB223245 inhibitor
D0596 RGD triazole-derived antagonists antagonist

Fibrosis Related Property

Reference Record 1

PubMed ID 27761847 Compound ID D0596
CAS Name RGD triazole-derived antagonists
Model vitro Fibrosis Disease Fibrosis
Process I
Process II EndMT
Process III
Mechanism

Reference Record 2

PubMed ID 18456735 Compound ID D0434
CAS 175529-44-9 Name SB223245
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Smad2