A-77

Basic Information

CAS ID: 607737-87-1
Molecular Formula: C18H14N4
Molecular Weight: 286.3 g/mol
Monoisotopic Mass: 286.1218 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N NH N N

Compound Structure and Identifier

InChI: InChI=1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H,1H3,(H,20,22) See All
InChI Key: KJTYZDORHCDZPS-UHFFFAOYSA-N
Smiles: Cc1cccc(n1)c2[nH]ncc2c3ccnc4ccccc34 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0007 TGF-beta receptor type-1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 18451253 Target ID T0007
Uniprot ID TGF-beta receptor type-1 Name TGF-beta receptor type-1
Model vitro,mice Fibrosis Disease Peribronchial fibrosis
Process I
Process II fibroblasts proliferation
Process III
Mechanism

Related Link

PubChem: 10469233
ChEMBL: CHEMBL129677