Fumagillin

Basic Information

CAS ID: 23110-15-8
Molecular Formula: C26H34O7
Molecular Weight: 458.6 g/mol
Monoisotopic Mass: 458.2305 g/mol
Class: Small Molecule
Natural Product: No
Other Names: FUMAGILLIN | FUMIDIL
Analysis: Drug repositioning mechanism analysis

O O O O O O OH

Compound Structure and Identifier

InChI: InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1 See All
InChI Key: NGGMYCMLYOUNGM-CSDLUJIJSA-N
Smiles: CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@H]1[C@@]3(C)O[C@@H]3CC=C(C)C)OC(=O)\C=C\C=C\C=C\C=C\C(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0513 Methionine aminopeptidase 2 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 17446530 Target ID T0513
Uniprot ID Methionine aminopeptidase 2 Name Methionine aminopeptidase 2
Model vitro,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 6917655
ChEMBL: CHEMBL32838