Methionine aminopeptidase 2

Basic Information


Uniprot ID: P50579
Secondary ID: B2RDI8
Symbol: METAP2
Other Name: MNPEP,MAP 2,MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67,p67eIF2,Peptidase M
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Aminopeptidase,Hydrolase,Protease


Target Classification


Category I Category II Category III
Intracellular Enzyme Protease

Related Compound


Target ID Name Interaction
D0449 Fumagillin inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 17446530 Compound ID D0449
CAS 23110-15-8 Name Fumagillin
Model vitro,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism