Doramapimod

Basic Information

CAS ID: 285983-48-4
Molecular Formula: C31H37N5O3
Molecular Weight: 527.7 g/mol
Monoisotopic Mass: 527.2896 g/mol
Class: Small Molecule
Natural Product: No
Other Names: BIRB-796 | DORAMAPIMOD
Analysis: Drug repositioning mechanism analysis

N N NH O NH O N O

Compound Structure and Identifier

InChI: InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37) See All
InChI Key: MVCOAUNKQVWQHZ-UHFFFAOYSA-N
Smiles: Cc1ccc(cc1)n2nc(cc2NC(=O)Nc3ccc(OCCN4CCOCC4)c5ccccc35)C(C)(C)C See All
Molfile: Download

Related Target

Target ID Name Interaction
T0985 p38 mitogen-activated protein kinases inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 17224470 Target ID T0985
Uniprot ID p38 mitogen-activated protein kinases Name p38 mitogen-activated protein kinases
Model rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 156422
ChEMBL: CHEMBL103667