p38 mitogen-activated protein kinases

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: pro-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Other

Related Compound

Target ID Name Interaction
D0350 FR167653 inhibitor
D0454 Doramapimod inhibitor
D0475 SB-239063AN inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 24332090 Compound ID
CAS Name
Model Fibrosis Disease Fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 17224470 Compound ID D0454
CAS 285983-48-4 Name Doramapimod
Model rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 16873723 Compound ID
CAS Name
Model Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 16849392 Compound ID
CAS Name
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 16841034 Compound ID D0110
CAS 152121-47-6 Name SB203580
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 15769460 Compound ID D0475
CAS 219790-72-4 Name SB-239063AN
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 7

PubMed ID 12077559 Compound ID D0110
CAS 152121-47-6 Name SB203580
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 8

PubMed ID 11728947 Compound ID D0350
CAS 158876-66-5 Name FR167653
Model vitro,rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism