Naringenin

Basic Information

CAS ID: 480-41-1
Molecular Formula: C15H12O5
Molecular Weight: 272.3 g/mol
Monoisotopic Mass: 272.0685 g/mol
Class: Small Molecule
Natural Product: No
Other Names: NSC-11855
Analysis: Drug repositioning mechanism analysis

HO O OH OH O

Compound Structure and Identifier

InChI: InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2/t13-/m0/s1 See All
InChI Key: FTVWIRXFELQLPI-ZDUSSCGKSA-N
Smiles: Oc1ccc(cc1)[C@@H]2CC(=O)c3c(O)cc(O)cc3O2 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0557 Mothers against decapentaplegic homolog 3 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 16341574 Target ID T0557
Uniprot ID Mothers against decapentaplegic homolog 3 Name Mothers against decapentaplegic homolog 3
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1-Smad3 signaling

Related Link

PubChem: 439246
ChEMBL: CHEMBL9352