Genistein

Basic Information

CAS ID: 446-72-0
Molecular Formula: C15H10O5
Molecular Weight: 270.2 g/mol
Monoisotopic Mass: 270.0528 g/mol
Class: Small Molecule
Natural Product: No
Other Names: NSC-36586
Analysis: Drug repositioning mechanism analysis

HO O OH OH O

Compound Structure and Identifier

InChI: InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H See All
InChI Key: TZBJGXHYKVUXJN-UHFFFAOYSA-N
Smiles: Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0986 Protein tyrosine kinase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 12174389 Target ID T0986
Uniprot ID Protein tyrosine kinase Name Protein tyrosine kinase
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation
Process III
Mechanism

Trial Record 1

ClinicalTrial ID NCT00016744 Disease Cystic fibrosis
Phase Phase 1,Phase 2 Status Completed
First Received June 4, 2001 Last Verified January 9, 2009
Sponsor Children's Hospital of Philadelphia

Trial Record 2

ClinicalTrial ID NCT00590538 Disease Cystic fibrosis
Phase Phase 1,Phase 2 Status Terminated
First Received January 10, 2008 Last Verified June 30, 2011
Sponsor Children's Hospital of Philadelphia

Related Link

PubChem: 5280961
ChEMBL: CHEMBL44