Sulforaphane

Basic Information

CAS ID: 4478-93-7
Molecular Formula: C6H11NOS2
Molecular Weight: 177.3 g/mol
Monoisotopic Mass: 177.0282 g/mol
Class: Small Molecule
Natural Product: No
Other Names: 4-(Methylsulfinyl)Butyl Isothiocyanate
Analysis: Drug repositioning mechanism analysis

S+ O- N S

Compound Structure and Identifier

InChI: InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3 See All
InChI Key: SUVMJBTUFCVSAD-UHFFFAOYSA-N
Smiles: C[S+]([O-])CCCCN=C=S See All
Molfile: Download

Related Target

Target ID Name Interaction
T0543 Nuclear factor erythroid 2-related factor 2 activator

Related Fibrosis Property

Reference Record 1

PubMed ID 26494449 Target ID T0543
Uniprot ID Nuclear factor erythroid 2-related factor 2 Name Nuclear factor erythroid 2-related factor 2
Model mice Fibrosis Disease Muscle fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β/Smad signaling

Reference Record 2

PubMed ID 24707343 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Aortic fibrosis
Process I attenue inflammation
Process II cells proliferation,cells apoptosis
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 22703534 Target ID T0543
Uniprot ID Nuclear factor erythroid 2-related factor 2 Name Nuclear factor erythroid 2-related factor 2
Model vitro,human,mice Fibrosis Disease Idiopathic pulmonary fibrosis
Process I
Process II fibroblasts proliferation,fibroblasts differentiation,fibroblasts migration
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 24967692 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Testicular fibrosis
Process I attenue inflammation
Process II cells proliferation,cells apoptosis
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 24707343 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Vascular fibrosis
Process I attenue inflammation
Process II cells proliferation,cells apoptosis
Process III prevenet collagen deposition
Mechanism

Trial Record 1

ClinicalTrial ID NCT01315665 Disease Cystic fibrosis
Phase Not Applicable Status Completed
First Received March 15, 2011 Last Verified February 15, 2019
Sponsor University Hospitals Cleveland Medical Center

Related Link

PubChem: 5350
ChEMBL: CHEMBL48802