LY364947

Basic Information

CAS ID: 396129-53-6
Molecular Formula: C17H12N4
Molecular Weight: 272.3 g/mol
Monoisotopic Mass: 272.1062 g/mol
Class: Small Molecule
Natural Product: No
Other Names: HTS-466284 | LY-364947
Analysis: Drug repositioning mechanism analysis

N N NH N

Compound Structure and Identifier

InChI: InChI=1S/C17H12N4/c1-2-6-15-13(5-1)12(8-10-19-15)14-11-20-21-17(14)16-7-3-4-9-18-16/h1-11H,(H,20,21) See All
InChI Key: IBCXZJCWDGCXQT-UHFFFAOYSA-N
Smiles: c1ccc(nc1)c2n[nH]cc2c3ccnc4ccccc34 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0007 TGF-beta receptor type-1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 22853924 Target ID T0007
Uniprot ID TGF-beta receptor type-1 Name TGF-beta receptor type-1
Model vitro,pig Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 447966
ChEMBL: CHEMBL261454