Captopril

Basic Information

CAS ID: 62571-86-2
Molecular Formula: C9H15NO3S
Molecular Weight: 217.3 g/mol
Monoisotopic Mass: 217.0773 g/mol
Class: Small Molecule
Natural Product: No
Other Names: CAPTOPRIL | CAPTOMEX | SQ 14,225 | HYTENEZE 25 | CAPOTEN | NOYADA | ACEPRIL | Lopril | HYTENEZE 12.5 | KAPLON | ECOPACE | HYTENEZE 50 | Tensobon
Analysis: Drug repositioning mechanism analysis

SH O N O HO

Compound Structure and Identifier

InChI: InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1 See All
InChI Key: FAKRSMQSSFJEIM-RQJHMYQMSA-N
Smiles: C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0213 Angiotensin-converting enzyme inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 11592866 Target ID T0213
Uniprot ID Angiotensin-converting enzyme Name Angiotensin-converting enzyme
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 20881240 Target ID
Uniprot ID Name
Model mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Trial Record 1

ClinicalTrial ID NCT00077064 Disease Pulmonary fibrosis
Phase Phase 2 Status Terminated
First Received February 11, 2004 Last Verified March 8, 2018
Sponsor Radiation Therapy Oncology Group

Related Link

PubChem: 44093
ChEMBL: CHEMBL1560