Benazepril

Basic Information

CAS ID: 86541-75-5
Molecular Formula: C24H28N2O5
Molecular Weight: 424.5 g/mol
Monoisotopic Mass: 424.1998 g/mol
Class: Small Molecule
Natural Product: No
Other Names: CGS-14824A | Lotrel | BENAZEPRIL | Lotensin | CIBACEN | LOTENSIN | BENAZEPRIL HYDROCHLORIDE | CGS 14824A HCL
Analysis: Drug repositioning mechanism analysis

O O NH N O OH O

Compound Structure and Identifier

InChI: InChI=1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1 See All
InChI Key: XPCFTKFZXHTYIP-PMACEKPBSA-N
Smiles: CCOC(=O)[C@H](CCc1ccccc1)N[C@H]2CCc3ccccc3N(CC(=O)O)C2=O See All
Molfile: Download

Related Target

Target ID Name Interaction
T0213 Angiotensin-converting enzyme inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 15339989 Target ID T0213
Uniprot ID Angiotensin-converting enzyme Name Angiotensin-converting enzyme
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 15149348 Target ID T0213
Uniprot ID Angiotensin-converting enzyme Name Angiotensin-converting enzyme
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 11867951 Target ID T0213
Uniprot ID Angiotensin-converting enzyme Name Angiotensin-converting enzyme
Model rat Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 40466887
ChEMBL: CHEMBL838