TCV-116

Basic Information

CAS ID: 145040-37-5
Molecular Formula: C33H34N6O6
Molecular Weight: 610.7 g/mol
Monoisotopic Mass: 610.254 g/mol
Class: Small Molecule
Natural Product: No
Other Names: ATACAND | TCV-116 | AMIAS | RATACAND | CANDESARTAN CILEXETIL | CANDESARTAN
Analysis: Drug repositioning mechanism analysis

O N O O O O O N N N NH N

Compound Structure and Identifier

InChI: InChI=1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38) See All
InChI Key: GHOSNRCGJFBJIB-UHFFFAOYSA-N
Smiles: CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc4ccc(cc4)c5ccccc5c6nn[nH]n6 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0118 Type-1 angiotensin II receptor antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 11847192 Target ID T0118
Uniprot ID Type-1 angiotensin II receptor Name Type-1 angiotensin II receptor
Model rat Fibrosis Disease Cardiac fibrosis
Process I attenue inflammation
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 2540
ChEMBL: CHEMBL1014