PF915275

Basic Information

CAS ID: 857290-04-1
Molecular Formula: C18H14N4O2S
Molecular Weight: 350.4 g/mol
Monoisotopic Mass: 350.084 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N NH S O O N H2N

Compound Structure and Identifier

InChI: InChI=1S/C18H14N4O2S/c19-12-13-4-6-14(7-5-13)15-8-10-16(11-9-15)25(23,24)22-18-3-1-2-17(20)21-18/h1-11H,(H3,20,21,22) See All
InChI Key: ZESFDAKNYJQYKO-UHFFFAOYSA-N
Smiles: C1=CC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)C#N)N See All
Molfile: Download

Related Target

Target ID Name Interaction
T0507 Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 29221204 Target ID T0507
Uniprot ID Corticosteroid 11-beta-dehydrogenase isozyme 1 Name Corticosteroid 11-beta-dehydrogenase isozyme 1
Model vitro,mice Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting EGFR

Related Link

PubChem: 23725123
ChEMBL: