Pifithrin-α

Basic Information

CAS ID: 63208-82-2
Molecular Formula: C16H19BrN2OS
Molecular Weight: 286.4 g/mol
Monoisotopic Mass: 286.114 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Pifithrin-Alpha
Analysis: Drug repositioning mechanism analysis

HBr O N NH S

Compound Structure and Identifier

InChI: InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H See All
InChI Key: HAGVCKULCLQGRF-UHFFFAOYSA-N
Smiles: Br.Cc1ccc(cc1)C(=O)CN2C(=N)SC3=C2CCCC3 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0613 Cellular tumor antigen p53 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 28240316 Target ID T0613
Uniprot ID Cellular tumor antigen p53 Name Cellular tumor antigen p53
Model vitro,human,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting STAT3

Related Link

PubChem: 9929138
ChEMBL: CHEMBL556353