L732138

Basic Information

CAS ID: 148451-96-1
Molecular Formula: C22H18F6N2O3
Molecular Weight: 472.4 g/mol
Monoisotopic Mass: 472.1222 g/mol
Class: Small Molecule
Natural Product: No
Other Names: L-732138
Analysis: Drug repositioning mechanism analysis

O NH NH O O F F F F F F

Compound Structure and Identifier

InChI: InChI=1S/C22H18F6N2O3/c1-12(31)30-19(8-14-10-29-18-5-3-2-4-17(14)18)20(32)33-11-13-6-15(21(23,24)25)9-16(7-13)22(26,27)28/h2-7,9-10,19,29H,8,11H2,1H3,(H,30,31)/t19-/m0/s1 See All
InChI Key: BYYQYXVAWXAYQC-IBGZPJMESA-N
Smiles: CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc3cc(cc(c3)C(F)(F)F)C(F)(F)F See All
Molfile: Download

Related Target

Target ID Name Interaction
T0151 Substance-P receptor antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 28647476 Target ID T0151
Uniprot ID Substance-P receptor Name Substance-P receptor
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,HSCs proliferation,HSC apoptosis
Process III
Mechanism

Related Link

PubChem: 132837
ChEMBL: CHEMBL22870