MG132

Basic Information

CAS ID: 133407-82-6
Molecular Formula: C26H41N3O5
Molecular Weight: 475.6 g/mol
Monoisotopic Mass: 475.305 g/mol
Class: Peptide
Natural Product: No
Other Names: MG-132
Analysis: Drug repositioning mechanism analysis

O NH O NH O NH O O

Compound Structure and Identifier

InChI: InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1 See All
InChI Key: TZYWCYJVHRLUCT-VABKMULXSA-N
Smiles: CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T1023 Proteasome inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 16440346 Target ID T1023
Uniprot ID Proteasome Name Proteasome
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs apoptosis
Process III
Mechanism

Reference Record 2

PubMed ID 16959829 Target ID T1023
Uniprot ID Proteasome Name Proteasome
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 3

PubMed ID 21175982 Target ID T1023
Uniprot ID Proteasome Name Proteasome
Model vitro,rat Fibrosis Disease Renal fibrosis
Process I
Process II myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism Targeting Smad

Related Link

PubChem: 462382
ChEMBL: CHEMBL64925