Ciglitazone

Basic Information

CAS ID: 74772-77-3
Molecular Formula: C18H23NO3S
Molecular Weight: 333.5 g/mol
Monoisotopic Mass: 333.1399 g/mol
Class: Peptide
Natural Product: No
Other Names: CIGLITAZONE | ADD-3878 | U-63287
Analysis: Drug repositioning mechanism analysis

O S O NH O

Compound Structure and Identifier

InChI: InChI=1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21) See All
InChI Key: YZFWTZACSRHJQD-UHFFFAOYSA-N
Smiles: CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0526 Peroxisome proliferator-activated receptor gamma agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 15734787 Target ID T0526
Uniprot ID Peroxisome proliferator-activated receptor gamma Name Peroxisome proliferator-activated receptor gamma
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I
Process II myofibroblasts differentiation
Process III
Mechanism

Reference Record 2

PubMed ID 18162602 Target ID T0526
Uniprot ID Peroxisome proliferator-activated receptor gamma Name Peroxisome proliferator-activated receptor gamma
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I
Process II fibroblasts proliferation,myofibroblasts differentiation
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 2750
ChEMBL: CHEMBL7002