Mitogen-activated protein kinase 3

Basic Information

Uniprot ID: P27361
Secondary ID: A8CZ58, B0LPG3, Q8NHX1
Symbol: MAPK3
Other Name: ERK1,MAP kinase 3,MAPK 3,ERT2,Extracellular signal-regulated kinase 1,ERK-1,Insulin-stimulated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,Microtubule-associated protein 2 kinase,p44-ERK1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Kinase,Serine/threonine-protein kinase,Transferase

Target Classification

Category I Category II Category III
Intracellular Enzyme Kinase

Related Compound

Target ID Name Interaction
D0035 PD98059 inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 25873302 Compound ID D0035
CAS 167869-21-8 Name PD98059
Model vitro Fibrosis Disease Pulmonary fibrosis
Process I
Process II EMT
Process III
Mechanism Targeting MAPK signaling

Reference Record 2

PubMed ID 16289155 Compound ID D0035
CAS 167869-21-8 Name PD98059
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III
Mechanism