Inhibitor of nuclear factor kappa-B kinase subunit alpha

Basic Information

Uniprot ID: O15111
Secondary ID: O14666
Symbol: CHUK
Other Name: IKKA,I-kappa-B kinase alpha,IKK-A,IKK-alpha,IkBKA,IkappaB kinase,Conserved helix-loop-helix ubiquitous kinase,I-kappa-B kinase 1,IKK1,Nuclear factor NF-kappa-B inhibitor kinase alpha,NFKBIKA,Transcription factor 16,TCF-16
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Kinase,Serine/threonine-protein kinase,Transferase

Target Classification

Category I Category II Category III
Intracellular Enzyme Kinase

Related Compound

Target ID Name Interaction
D0580 Sulfasalazine inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 15633128 Compound ID D0580
CAS 599-79-1 Name Sulfasalazine
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II HSCs apoptosis
Process III
Mechanism