Poly [ADP-ribose] polymerase tankyrase-2

Basic Information


Uniprot ID: Q9H2K2
Secondary ID: B2RBD3, Q9H8F2, Q9HAS4
Symbol: TNKS2
Other Name: PARP5B,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,Protein poly-ADP-ribosyltransferase tankyrase-2,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-2,TANK2,Tankyrase-like protein,Tankyrase-related protein
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Glycosyltransferase,Transferase


Target Classification


Category I Category II Category III
Intracellular Enzyme Transferase

Related Compound


Target ID Name Interaction
D0322 XAV-939 inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 23148305 Compound ID D0322
CAS 284028-89-3 Name XAV-939
Model mice Fibrosis Disease Dermal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Wnt signaling