XAV-939

Basic Information

CAS ID: 284028-89-3
Molecular Formula: C14H11F3N2OS
Molecular Weight: 312.3 g/mol
Monoisotopic Mass: 312.0544 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

OH N N S F F F

Compound Structure and Identifier

InChI: InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) See All
InChI Key: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Smiles: Oc1nc(nc2CCSCc12)c3ccc(cc3)C(F)(F)F See All
Molfile: Download

Related Target

Target ID Name Interaction
T0469 Poly [ADP-ribose] polymerase tankyrase-1 inhibitor
T0470 Poly [ADP-ribose] polymerase tankyrase-2 inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 23148305 Target ID T0470
Uniprot ID Poly [ADP-ribose] polymerase tankyrase-2 Name Poly [ADP-ribose] polymerase tankyrase-2
Model mice Fibrosis Disease Dermal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Wnt signaling

Reference Record 2

PubMed ID 23148305 Target ID T0469
Uniprot ID Poly [ADP-ribose] polymerase tankyrase-1 Name Poly [ADP-ribose] polymerase tankyrase-1
Model mice Fibrosis Disease Dermal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism Targeting Wnt signaling

Related Link

PubChem: 2726824
ChEMBL: CHEMBL1086580