Nuclear receptor subfamily 1 group D member 2

Basic Information


Uniprot ID: Q14995
Secondary ID: B2R8Q3, O00402, Q86XD4
Symbol: NR1D2
Other Name: Orphan nuclear hormone receptor BD73,Rev-erb alpha-related receptor,RVR,Rev-erb-beta,V-erbA-related protein 1-related,EAR-1R
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,DNA-binding,Receptor,Repressor


Target Classification


Category I Category II Category III
Intracellular Nuclear receptor NR1 family

Related Compound


Target ID Name Interaction
D0521 SR8278 antagonist

Fibrosis Related Property


Reference Record 1

PubMed ID 29215066 Compound ID D0521
CAS 1254944-66-5 Name SR8278
Model vitro,mice Fibrosis Disease Muscle fibrosis
Process I
Process II cells activation,cells differentiation
Process III prevenet collagen deposition
Mechanism